S100 Calcium Binding Protein A4 (S100A4)

[Edit]

S100-A4; MTS1; 18A2; 42A; CAPL; P9KA; PEL98; Calcium protein; Calvasculin; Metastasin; Protein Mts1; Placental calcium-binding protein; Murine placental homolog

S100 Calcium Binding Protein A4 (S100A4)

S100 calcium binding protein A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.

This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC020Hu01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC020Hu01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC
LAC020Hu71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC.
LAC020Hu81 FITC-Linked Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
MAC020Hu21 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
Assay Kits SEC020Mi ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.
SEC020Hu ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.
HEC020Hu High Sensitive ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC020Mu01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
RPC020Mu02 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC020Mu01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
LAC020Mu71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC.
LAC020Mu81 FITC-Linked Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IF.
PAC020Mu02 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
Assay Kits SEC020Mi ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.
SEC020Mu ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC020Ra01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC020Ra01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
MAC020Ra21 Monoclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
Assay Kits SEC020Mi ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.
SEC020Ra ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC020Bo01 Recombinant S100 Calcium Binding Protein A4 (S100A4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC020Bo01 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC; IP.
LAC020Bo71 Biotin-Linked Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for S100 Calcium Binding Protein A4 (S100A4) CLIA Kit Customized Service Offer
n/a ELISA Kit for S100 Calcium Binding Protein A4 (S100A4) ELISA Kit Customized Service Offer
  1. "S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart."Biochemistry 31:10258-10264(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E."Proc. Natl. Acad. Sci. U.S.A. 90:6547-6551(1993) [PubMed] [Europe PMC] [Abstract]
  3. "Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences."Proc. Natl. Acad. Sci. U.S.A. 89:9146-9150(1992) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Calcyclin and calvasculin exist in human platelets."Biochem. Biophys. Res. Commun. 189:1310-1316(1992) [PubMed] [Europe PMC] [Abstract]
  8. "Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)."J. Biol. Chem. 277:5229-5235(2002) [PubMed] [Europe PMC] [Abstract]
  9. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy."Biochemistry 41:12670-12680(2002) [PubMed] [Europe PMC] [Abstract]