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Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5)

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HLA-DRB5; HLADRb5; Dw2; HLA Class II Histocompatibility Antigen,DRB5 Beta Chain

Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5)
CCC C088
HGNC 4953
PubMed 2989367
UniProt Q30154
Wiki HLA-DRB5
HLA class II histocompatibility antigen, DRB5 beta chain belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells.DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Class II DR Beta 5 (MHCDRb5) ELISA Kit Customized Service Offer
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