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Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1)

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HLA-DQB1; HLADQb1; CELIAC1; HLA-DQB; IDDM1; HLA Class II Histocompatibility Antigen,DQ Beta 1 Chain

Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1)
CCC C165
HGNC 4944
MGI 103070
PubMed 17190762
UniProt P01918
Wiki HLA-DQB1

Major histocompatibility complex, class II, DQ beta 1 is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins.

The beta chain is approximately 26-28 kDa and it contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular protein domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC165Hu01 Recombinant Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC165Hu01 Polyclonal Antibody to Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) WB; IHC; ICC; IP.
MAC165Hu21 Monoclonal Antibody to Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) WB; IHC; ICC; IP.
Assay Kits SEC165Hu ELISA Kit for Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC165Mu01 Recombinant Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC165Mu02 Recombinant Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC165Mu01 Polyclonal Antibody to Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) WB; IHC; ICC; IP.
PAC165Mu02 Polyclonal Antibody to Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) WB; IHC; ICC; IP.
Assay Kits SEC165Mu ELISA Kit for Major Histocompatibility Complex Class II DQ Beta 1 (MHCDQb1) Enzyme-linked immunosorbent assay for Antigen Detection.
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