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Tropomyosin Receptor Kinase B (TrkB)

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GP145-TrkB; NTRK2; BDNF/NT-3 growth factors receptor; Neurotrophic Tyrosine Kinase Receptor Type 2; Tropomyosin-related kinase B; TrkB tyrosine kinase

Tropomyosin Receptor Kinase B (TrkB)
CCC C183
HGNC 8032
MGI 97384
PubMed 15838534
RGD 3213
UniProt Q16620
Wiki NTRK2

TrkB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The neurotrophins that activate TrkB are: Brain Derived Neurotrophic Factor, or "BDNF", NT-4 (neurotrophin-4), and NT-3 (neurotrophin-3). As such, TrkB mediates the multiple effects of these neurotrophic factors, which includes neuronal differentiation and survival. The TrkB receptor is part of the large family of receptor tyrosine kinases. A "tyrosine kinase" is an enzyme which is capable of adding a phosphate group to certain tyrosines on target proteins, or "substrates". A receptor tyrosine kinase is a "tyrosine kinase" which is located at the cellular membrane, and is activated by binding of a ligand to the receptor's extracellular domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC183Hu01 Recombinant Tropomyosin Receptor Kinase B (TrkB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC183Hu01 Polyclonal Antibody to Tropomyosin Receptor Kinase B (TrkB) WB; IHC; ICC; IP.
Assay Kits SEC183Hu ELISA Kit for Tropomyosin Receptor Kinase B (TrkB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tropomyosin Receptor Kinase B (TrkB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tropomyosin Receptor Kinase B (TrkB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tropomyosin Receptor Kinase B (TrkB) Polyclonal Antibody Customized Service Offer
Assay Kits SEC183Mu ELISA Kit for Tropomyosin Receptor Kinase B (TrkB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tropomyosin Receptor Kinase B (TrkB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tropomyosin Receptor Kinase B (TrkB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tropomyosin Receptor Kinase B (TrkB) Polyclonal Antibody Customized Service Offer
Assay Kits SEC183Ra ELISA Kit for Tropomyosin Receptor Kinase B (TrkB) Enzyme-linked immunosorbent assay for Antigen Detection.
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