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Host Cell Factor C1 (HCFC1)

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HCF-C1; CFF; HCF1; HCF1; HFC1; VCAF; VP16-Accessory Protein

Host Cell Factor C1 (HCFC1)
CCC C209
HGNC 4839
MGI 105942
PubMed 23539139
RGD 1563804
UniProt P51610
Wiki HCFC1
Host cell factor is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain.
The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC209Hu01 Recombinant Host Cell Factor C1 (HCFC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC209Hu01 Polyclonal Antibody to Host Cell Factor C1 (HCFC1) WB,IHC
Assay Kits n/a CLIA Kit for Host Cell Factor C1 (HCFC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Host Cell Factor C1 (HCFC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC209Mu01 Recombinant Host Cell Factor C1 (HCFC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC209Mu01 Polyclonal Antibody to Host Cell Factor C1 (HCFC1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Host Cell Factor C1 (HCFC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Host Cell Factor C1 (HCFC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Host Cell Factor C1 (HCFC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Host Cell Factor C1 (HCFC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Host Cell Factor C1 (HCFC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Host Cell Factor C1 (HCFC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Host Cell Factor C1 (HCFC1) ELISA Kit Customized Service Offer
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  40. "Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex."J. Biol. Chem. 285:4268-4272(2010) [PubMed] [Europe PMC] [Abstract]
  41. "The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias."J. Biol. Chem. 285:13364-13371(2010) [PubMed] [Europe PMC] [Abstract]
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  48. "TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS."EMBO J. 32:645-655(2013) [PubMed] [Europe PMC] [Abstract]
  49. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  50. "A noncoding, regulatory mutation implicates HCFC1 in nonsyndromic intellectual disability."Am. J. Hum. Genet. 91:694-702(2012) [PubMed] [Europe PMC] [Abstract]