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C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1)

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RAF1; CRAF; V-raf-1 Murine Leukemia Viral Oncogene Homolog 1; Proto-oncogene c-RAF

C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1)
CCC C232
HGNC 9829
MGI 97847
PubMed 7803760
RGD 3531
UniProt P04049
Wiki C-Raf

C-raf is gene that codes for a protein kinase. That protein is sometimes called c-Raf and will be called "Raf-1" here. The Raf-1 protein functions in the MAPK/ERK signal transduction pathway as part of a protein kinase cascade. Raf-1 is a serine/threonine-specific kinase.Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC232Hu01 Recombinant C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC232Hu01 Polyclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) WB; IHC; ICC; IP.
MAC232Hu22 Monoclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) WB; IHC; ICC; IP.
Assay Kits SEC232Hu ELISA Kit for C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) CLIA Kit Customized Service Offer
n/a ELISA Kit for C-Raf Proto Oncogene Serine/Threonine Protein Kinase (Raf-1) ELISA Kit Customized Service Offer
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