Wilms Tumor 1 Associated Protein (WTAP)
[Edit]hFL(2)D; Pre-mRNA-Splicing Regulator WTAP; Female-lethal(2)D homolog; WT1-associated protein
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The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein.
Like WT1 protein, Pre-mRNA-splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA- binding ability and inhibits expression of WT1 target genes. May be involved in mRNA splicing regulation.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC245Hu01 | Recombinant Wilms Tumor 1 Associated Protein (WTAP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC245Hu01 | Polyclonal Antibody to Wilms Tumor 1 Associated Protein (WTAP) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Wilms Tumor 1 Associated Protein (WTAP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Wilms Tumor 1 Associated Protein (WTAP) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Wilms Tumor 1 Associated Protein (WTAP) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Wilms Tumor 1 Associated Protein (WTAP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Wilms Tumor 1 Associated Protein (WTAP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Wilms Tumor 1 Associated Protein (WTAP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Wilms Tumor 1 Associated Protein (WTAP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Wilms Tumor 1 Associated Protein (WTAP) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Wilms Tumor 1 Associated Protein (WTAP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Wilms Tumor 1 Associated Protein (WTAP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Wilms Tumor 1 Associated Protein (WTAP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Wilms Tumor 1 Associated Protein (WTAP) | ELISA Kit Customized Service Offer |
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