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Erythrocyte Membrane Protein Band 4.1 (EPB41)

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EL1; EPB41; 4.1R; HE; Elliptocytosis 1,RH-linked

Erythrocyte Membrane Protein Band 4.1 (EPB41)
CCC C264
HGNC 3377
MGI 95401
PubMed 15475241
RGD 1564762
UniProt P11171
Wiki EPB41

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton.

The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene , the beta-spectrin gene , or the band 3 gene .Band 4.1 is a protein associated with the cytoskeleton of the red blood cell.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC264Hu01 Recombinant Erythrocyte Membrane Protein Band 4.1 (EPB41) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC264Hu01 Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) CLIA Kit Customized Service Offer
n/a ELISA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC264Mu01 Recombinant Erythrocyte Membrane Protein Band 4.1 (EPB41) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC264Mu01 Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) CLIA Kit Customized Service Offer
n/a ELISA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Erythrocyte Membrane Protein Band 4.1 (EPB41) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 (EPB41) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) CLIA Kit Customized Service Offer
n/a ELISA Kit for Erythrocyte Membrane Protein Band 4.1 (EPB41) ELISA Kit Customized Service Offer
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  17. "Mitotic regulation of protein 4.1R involves phosphorylation by cdc2 kinase."Mol. Biol. Cell 16:117-127(2005) [PubMed] [Europe PMC] [Abstract]
  18. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  19. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  20. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  21. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  22. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  23. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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