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Attractin (ATRN)

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DPPT-L; MGCA; Mahogany homolog

Attractin (ATRN)
CCC C304
HGNC 885
MGI 1341628
PubMed 11137996
RGD 69063
UniProt O75882
Wiki ATRN
Attractin is a protein encoded by the ATRN gene.Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2/secreted is the major isoform in peripheral blood leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC304Hu01 Recombinant Attractin (ATRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC304Hu01 Polyclonal Antibody to Attractin (ATRN) WB; IHC; ICC; IP.
MAC304Hu22 Monoclonal Antibody to Attractin (ATRN) WB; IHC; ICC; IP.
Assay Kits SEC304Hu ELISA Kit for Attractin (ATRN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Attractin (ATRN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Attractin (ATRN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Attractin (ATRN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Attractin (ATRN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Attractin (ATRN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Attractin (ATRN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Attractin (ATRN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Attractin (ATRN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Attractin (ATRN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Attractin (ATRN) ELISA Kit Customized Service Offer
  1. "Secreted and membrane attractin result from alternative splicing of the human ATRN gene."Proc. Natl. Acad. Sci. U.S.A. 97:6025-6030(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26)."J. Biol. Chem. 270:14107-14114(1995) [PubMed] [Europe PMC] [Abstract]
  6. "Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions."Proc. Natl. Acad. Sci. U.S.A. 95:11336-11341(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  8. "Does human attractin have DP4 activity?"Biol. Chem. 388:155-162(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."Proteomics 4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  11. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  12. "A strategy for precise and large scale identification of core fucosylated glycoproteins."Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]