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Ancient Ubiquitous Protein 1 (AUP1)

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Ancient Ubiquitous Protein 1 (AUP1)
CCC C307
HGNC 891
MGI 107789
PubMed 21127063
RGD 1591777
UniProt Q9Y679
Wiki AUP1

Ancient ubiquitous protein 1 is a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes.

The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. AUP1 in lipid droplets, and perhaps at the ER, has a role in ubiquitin-mediated protein degradation by recruiting UBE2G2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC307Hu01 Recombinant Ancient Ubiquitous Protein 1 (AUP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC307Hu01 Polyclonal Antibody to Ancient Ubiquitous Protein 1 (AUP1) WB,IHC
Assay Kits n/a CLIA Kit for Ancient Ubiquitous Protein 1 (AUP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ancient Ubiquitous Protein 1 (AUP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC307Mu01 Recombinant Ancient Ubiquitous Protein 1 (AUP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC307Mu01 Polyclonal Antibody to Ancient Ubiquitous Protein 1 (AUP1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ancient Ubiquitous Protein 1 (AUP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ancient Ubiquitous Protein 1 (AUP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ancient Ubiquitous Protein 1 (AUP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ancient Ubiquitous Protein 1 (AUP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ancient Ubiquitous Protein 1 (AUP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ancient Ubiquitous Protein 1 (AUP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ancient Ubiquitous Protein 1 (AUP1) ELISA Kit Customized Service Offer
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  13. "Solution structure of RSGI RUH-075, a human CUE domain."Submitted (SEP-2007) to the PDB data bank