Annexin A6 (ANXA6)
[Edit]ANX6; ANX-A6; CBP68; CPB-II; Annexin VI; 67 kDa calelectrin; Calphobindin-II; Chromobindin-20; Lipocortin VI
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC345Hu01 | Recombinant Annexin A6 (ANXA6) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC345Hu01 | Polyclonal Antibody to Annexin A6 (ANXA6) | WB; IHC; ICC; IP. |
MAC345Hu22 | Monoclonal Antibody to Annexin A6 (ANXA6) | WB; IHC; ICC; IP. | |
Assay Kits | SEC345Hu | ELISA Kit for Annexin A6 (ANXA6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC345Mu01 | Recombinant Annexin A6 (ANXA6) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC345Mu01 | Polyclonal Antibody to Annexin A6 (ANXA6) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Annexin A6 (ANXA6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Annexin A6 (ANXA6) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Annexin A6 (ANXA6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Annexin A6 (ANXA6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Annexin A6 (ANXA6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Annexin A6 (ANXA6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Annexin A6 (ANXA6) | ELISA Kit Customized Service Offer |
- "Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family."EMBO J. 7:21-27(1988) [PubMed] [Europe PMC] [Abstract]
- "Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins."Proc. Natl. Acad. Sci. U.S.A. 85:664-668(1988) [PubMed] [Europe PMC] [Abstract]
- "Structure and expression of cDNA for calphobindin II, a human placental coagulation inhibitor."J. Biochem. 106:43-49(1989) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Structure and properties of calphobindin II, an anticoagulant protein from human placenta."J. Biochem. 107:43-50(1990) [PubMed] [Europe PMC] [Abstract]
- "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."Biochem. J. 383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
- "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
- "The structure of recombinant human annexin VI in crystals and membrane-bound."J. Mol. Biol. 260:638-643(1996) [PubMed] [Europe PMC] [Abstract]