-92393.jpg)
Cortistatin, also known as CORT, is a neuropeptide with strong structural similarity to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity.
However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC393Hu01 | Recombinant Cortistatin (CORT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPC393Hu21 | OVA Conjugated Cortistatin (CORT) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAC393Hu01 | Polyclonal Antibody to Cortistatin (CORT) | WB; IHC; ICC; IP. |
| MAC393Hu22 | Monoclonal Antibody to Cortistatin (CORT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEC393Hu | ELISA Kit for Cortistatin (CORT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Cortistatin (CORT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Cortistatin (CORT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Cortistatin (CORT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | CEC393Mu | ELISA Kit for Cortistatin (CORT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Cortistatin (CORT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Cortistatin (CORT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Cortistatin (CORT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Cortistatin (CORT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cortistatin (CORT) | ELISA Kit Customized Service Offer |
- "Identification and characterization of a novel human cortistatin-like peptide."Biochem. Biophys. Res. Commun. 232:157-163(1997) [PubMed] [Europe PMC] [Abstract]
- "Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin."Genomics 42:499-506(1997) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]