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Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1)

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CEBP; CPE-BP1; CPEB

Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1)
CCC C396
HGNC 21744
MGI 108442
PubMed 23434754
RGD 1310421
UniProt Q9BZB8
Wiki CPEB1

Cytoplasmic polyadenylation element-binding protein 1 is  a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs.

Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC396Hu01 Recombinant Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC396Hu01 Polyclonal Antibody to Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) ELISA Kit Customized Service Offer
  1. "Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein."Gene 263:113-120(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1."Genes Cells 10:627-638(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules."J. Cell Sci. 118:981-992(2005) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "The C-Terminal region of cytoplasmic polyadenylation element binding protein is a ZZ domain with potential for protein-protein interactions."J. Mol. Biol. 425:2015-2026(2013) [PubMed] [Europe PMC] [Abstract]