FK506 Binding Protein 2 (FKBP2)
[Edit]FK-BP2; FKBP13; Peptidyl-Prolyl Cis-Trans Isomerase; Rapamycin-Binding Protein; Proline Isomerase; 13 kDa FK506-binding protein; Immunophilin FKBP13; Rotamase
-92479.jpg)
FK506-binding protein 2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin.
It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC479Hu01 | Recombinant FK506 Binding Protein 2 (FKBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC479Hu01 | Polyclonal Antibody to FK506 Binding Protein 2 (FKBP2) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for FK506 Binding Protein 2 (FKBP2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for FK506 Binding Protein 2 (FKBP2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant FK506 Binding Protein 2 (FKBP2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to FK506 Binding Protein 2 (FKBP2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to FK506 Binding Protein 2 (FKBP2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for FK506 Binding Protein 2 (FKBP2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for FK506 Binding Protein 2 (FKBP2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant FK506 Binding Protein 2 (FKBP2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to FK506 Binding Protein 2 (FKBP2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to FK506 Binding Protein 2 (FKBP2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for FK506 Binding Protein 2 (FKBP2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for FK506 Binding Protein 2 (FKBP2) | ELISA Kit Customized Service Offer |
- "Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13."Proc. Natl. Acad. Sci. U.S.A. 88:6677-6681(1991) [PubMed] [Europe PMC] [Abstract]
- "Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13."Biochem. Biophys. Res. Commun. 189:819-823(1992) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506."Proc. Natl. Acad. Sci. U.S.A. 100:2322-2327(2003) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]