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Flotillin 2 (FLOT2)

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ECS1; ESA; ESA1; M17S1; Epidermal Surface Antigen 1; Membrane Component,Chromosome 17,Surface Marker 1; 35kD Protein Identified By Monoclonal Antibody ECS-1

Flotillin 2 (FLOT2)
CCC C480
HGNC 3758
MGI 103309
PubMed 23146906
RGD 70993
UniProt Q14254
Wiki FLOT2
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Flotillin-2 is a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.
Human epidermal surface antigen-1 was identified as a 35-kD antigen by means of a mouse monoclonal antibody raised against human keratinocytes. The monoclonal antibody was found to cause keratinocyte dissociation in vitro; hence, the conclusion that the native protein is involved in cell adhesion. The mouse and human 5-prime- and 3-prime untranslated sequences are conserved. Similar RNA folding patterns of the 5-prime untranslated region are predicted despite a 91-bp insertion in the mouse.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC480Hu01 Recombinant Flotillin 2 (FLOT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC480Hu01 Polyclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
MAC480Hu22 Monoclonal Antibody to Flotillin 2 (FLOT2) WB; IHC; ICC; IP.
Assay Kits SEC480Hu ELISA Kit for Flotillin 2 (FLOT2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Flotillin 2 (FLOT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Flotillin 2 (FLOT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Flotillin 2 (FLOT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Flotillin 2 (FLOT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Flotillin 2 (FLOT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Flotillin 2 (FLOT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Flotillin 2 (FLOT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Flotillin 2 (FLOT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Flotillin 2 (FLOT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Flotillin 2 (FLOT2) ELISA Kit Customized Service Offer
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of a novel epidermal cell surface antigen (ESA)."J. Biol. Chem. 269:19983-19991(1994) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components."J. Biol. Chem. 285:31616-31633(2010) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells."J. Biol. Chem. 287:523-530(2012) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]