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Luteinizing Hormone Beta Polypeptide (LHb)

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LH-B; CGB4; LSH-B; hLHB; Lutropin Subunit Beta; Interstitial Cell Stimulating Hormone,Beta Chain

Luteinizing Hormone Beta Polypeptide (LHb)
CCC C579
HGNC 6584
MGI 96782
PubMed 2422163
RGD 3006
UniProt P01229
Wiki LHB
Lutropin subunit beta is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and a unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC579Hu01 Recombinant Luteinizing Hormone Beta Polypeptide (LHb) Positive Control; Immunogen; SDS-PAGE; WB.
EPC579Hu61 Eukaryotic Luteinizing Hormone Beta Polypeptide (LHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC579Hu01 Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
MAC579Hu21 Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
MAC579Hu22 Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
MAC579Hu23 Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
Assay Kits CEC579Hu ELISA Kit for Luteinizing Hormone Beta Polypeptide (LHb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC579Mu01 Recombinant Luteinizing Hormone Beta Polypeptide (LHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Luteinizing Hormone Beta Polypeptide (LHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Luteinizing Hormone Beta Polypeptide (LHb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC579Ra01 Recombinant Luteinizing Hormone Beta Polypeptide (LHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC579Ra01 Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
MAC579Ra22 Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
LAC579Ra71 Biotin-Linked Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC.
MAC579Ra21 Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Luteinizing Hormone Beta Polypeptide (LHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Luteinizing Hormone Beta Polypeptide (LHb) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Luteinizing Hormone Beta Polypeptide (LHb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) Polyclonal Antibody Customized Service Offer
Assay Kits CEC579Po ELISA Kit for Luteinizing Hormone Beta Polypeptide (LHb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC579Fi01 Recombinant Luteinizing Hormone Beta Polypeptide (LHb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC579Fi01 Polyclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Luteinizing Hormone Beta Polypeptide (LHb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Luteinizing Hormone Beta Polypeptide (LHb) ELISA Kit Customized Service Offer
  1. "Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone."Nature 307:37-40(1984) [PubMed] [Europe PMC] [Abstract]
  2. "Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit."Biochim. Biophys. Acta 412:70-81(1975) [PubMed] [Europe PMC] [Abstract]
  3. "The primary structure of the hormone-specific, beta subunit of human pituitary luteinizing hormone (hLH)."J. Clin. Endocrinol. Metab. 36:618-621(1973) [PubMed] [Europe PMC] [Abstract]
  4. "Structure and significance of human luteinizing hormone-beta core fragment purified from human pituitary extracts."Endocrinology 133:985-989(1993) [PubMed] [Europe PMC] [Abstract]
  5. "Human luteinizing hormone. The amino acid sequence of the subunit."FEBS Lett. 29:97-100(1973) [PubMed] [Europe PMC] [Abstract]
  6. "NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin."Eur. J. Biochem. 195:257-268(1991) [PubMed] [Europe PMC] [Abstract]
  7. "Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy."Mol. Endocrinol. 6:904-913(1992) [PubMed] [Europe PMC] [Abstract]
  8. "Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone."N. Engl. J. Med. 326:179-183(1992) [PubMed] [Europe PMC] [Abstract]
  9. "A new molecular variant of luteinizing hormone associated with female infertility."Fertil. Steril. 69:102-106(1998) [PubMed] [Europe PMC] [Abstract]
  10. "Increased prevalence of luteinizing hormone beta-subunit variant in Japanese infertility patients."Hum. Reprod. 13:3338-3344(1998) [PubMed] [Europe PMC] [Abstract]
  11. "A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone."Mol. Hum. Reprod. 8:201-212(2002) [PubMed] [Europe PMC] [Abstract]