Uroplakin 1A (UPK1A)

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UPK1-A; TSPAN21; UP1A; UPIA; UPKA; Tetraspanin-21; Uroplakin Ia

Uroplakin 1A (UPK1A)
Uroplakin-1a is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC588Hu01 Recombinant Uroplakin 1A (UPK1A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC588Hu01 Polyclonal Antibody to Uroplakin 1A (UPK1A) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Uroplakin 1A (UPK1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Uroplakin 1A (UPK1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC588Mu01 Recombinant Uroplakin 1A (UPK1A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC588Mu01 Polyclonal Antibody to Uroplakin 1A (UPK1A) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Uroplakin 1A (UPK1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Uroplakin 1A (UPK1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Uroplakin 1A (UPK1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Uroplakin 1A (UPK1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Uroplakin 1A (UPK1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Uroplakin 1A (UPK1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Uroplakin 1A (UPK1A) ELISA Kit Customized Service Offer
  1. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Transcriptional control of the human urothelial-specific gene, uroplakin Ia."Biochim. Biophys. Acta 1729:126-134(2005) [PubMed] [Europe PMC] [Abstract]
  4. "Uroplakin gene expression by normal and neoplastic human urothelium."Am. J. Pathol. 153:1957-1967(1998) [PubMed] [Europe PMC] [Abstract]