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Mitofusin 1 (MFN1)

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Hfzo1; Hfzo2; Transmembrane GTPase MFN1; Fzo homolog

Mitofusin 1 (MFN1)
CCC C619
HGNC 18262
MGI 1914664
PubMed 24626641
RGD 621460
UniProt Q8IWA4
Wiki MFN1
Mitofusin-1 is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
The deduced 741-amino acid protein contains an N-terminal GTPase domain and a transmembrane domain near the C terminus. MFN1 shares 60% identity with MFN2, with the most extensive homology in the GTPase domains. The N- and C-terminal ends are more variable. When stably expressed in COS-7 cells, MFN1 colocalized with mitochondrial markers. Overexpression of MFN1 caused perinuclear mitochondrial clustering.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC619Hu01 Recombinant Mitofusin 1 (MFN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC619Hu01 Polyclonal Antibody to Mitofusin 1 (MFN1) WB; IHC
Assay Kits SEC619Hu ELISA Kit for Mitofusin 1 (MFN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC619Mu01 Recombinant Mitofusin 1 (MFN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC619Mu01 Polyclonal Antibody to Mitofusin 1 (MFN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Mitofusin 1 (MFN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitofusin 1 (MFN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitofusin 1 (MFN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitofusin 1 (MFN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitofusin 1 (MFN1) Polyclonal Antibody Customized Service Offer
Assay Kits SEC619Ra ELISA Kit for Mitofusin 1 (MFN1) Enzyme-linked immunosorbent assay for Antigen Detection.
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