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Membrane Protein, Palmitoylated 1 (MPP1)

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MRG1; AAG12; EMP55; PEMP; 55 kDa Erythrocyte Membrane Protein

Membrane Protein, Palmitoylated 1 (MPP1)
CCC C624
HGNC 7219
MGI 105941
PubMed 8954807
UniProt Q00013
Wiki MPP1
Palmitoylated membrane protein 1 the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Protein, Palmitoylated 1 (MPP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Protein, Palmitoylated 1 (MPP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Protein, Palmitoylated 1 (MPP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Protein, Palmitoylated 1 (MPP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Protein, Palmitoylated 1 (MPP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Protein, Palmitoylated 1 (MPP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Protein, Palmitoylated 1 (MPP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Protein, Palmitoylated 1 (MPP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Protein, Palmitoylated 1 (MPP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Protein, Palmitoylated 1 (MPP1) ELISA Kit Customized Service Offer
  1. "Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif."Proc. Natl. Acad. Sci. U.S.A. 88:6595-6599(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The gene encoding the palmitoylated erythrocyte membrane protein, p55, originates at the CpG island 3' to the factor VIII gene."Hum. Mol. Genet. 1:97-101(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "MPP1 links the Usher protein network and the Crumbs protein complex in the retina."Hum. Mol. Genet. 16:1993-2003(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin."Exp. Biol. Med. 234:255-262(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells."J. Biol. Chem. 287:18974-18984(2012) [PubMed] [Europe PMC] [Abstract]
  12. "Solution structure of human erythroid p55 PDZ domain."Proteins 64:804-807(2006) [PubMed] [Europe PMC] [Abstract]