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Metadherin (MTDH)

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3D3; AEG1; LYRIC; Astrocyte elevated gene-1 protein; Lysine-rich CEACAM1 co-isolated protein; Metastasis adhesion protein

Metadherin (MTDH)
CCC C631
HGNC 29608
MGI 1914404
PubMed 15093543
RGD 620992
UniProt Q86UE4
Wiki MTDH
Elevated expression of the metastasis gene metadherin (MTDH), which is overexpressed in more than 40% of breast cancers, is associated with poor clinical outcomes. MTDH has a dual role in promoting metastatic seeding and enhancing chemoresistance.
MTDH is therefore a potential therapeutic target for enhancing chemotherapy and reducing metastasis. Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC631Hu01 Recombinant Metadherin (MTDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC631Hu01 Polyclonal Antibody to Metadherin (MTDH) WB; IHC; ICC; IP.
MAC631Hu22 Monoclonal Antibody to Metadherin (MTDH) WB; IHC; ICC; IP.
Assay Kits SEC631Hu ELISA Kit for Metadherin (MTDH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Metadherin (MTDH) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Metadherin (MTDH) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Metadherin (MTDH) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Metadherin (MTDH) CLIA Kit Customized Service Offer
n/a ELISA Kit for Metadherin (MTDH) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Metadherin (MTDH) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Metadherin (MTDH) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Metadherin (MTDH) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Metadherin (MTDH) CLIA Kit Customized Service Offer
n/a ELISA Kit for Metadherin (MTDH) ELISA Kit Customized Service Offer
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  14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
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