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Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP)

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Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP)
CCC C652
HGNC 7644
MGI 1355328
PubMed 1426632
RGD 1359609
UniProt P49321
Wiki NASP_(gene
Nuclear autoantigenic sperm protein is a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene.
The protein sequence is 53% identical to that of the Xenopus ortholog, and 85% identical to that of the rabbit ortholog when the N terminal of the rabbit sequence is aligned with amino acid 101 of the human sequence. Two histone-binding domains are strongly conserved. Northern blot analysis revealed a 3.2 kb mRNA. Immunolocalization experiments demonstrated that in the testis, NASP is found primarily in the cytoplasm of primary spermatocytes and around or within the nuclei of spermatids. NASP is present near the acrosomal region in mature human sperm.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC652Hu01 Recombinant Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC652Ra01 Recombinant Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC652Ra01 Polyclonal Antibody to Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) ELISA Kit Customized Service Offer
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  8. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
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  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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  16. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]