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Neuron Navigator 1 (NAV1)

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POMFIL3; unc53H1; Steerin-1; Pore Membrane and/or Filament Interacting Like Protein 3; Unc-53 homolog 1

Neuron Navigator 1 (NAV1)
CCC C653
HGNC 15989
MGI 2183683
PubMed 15797708
UniProt Q8NEY1
Wiki NAV1
Neuron navigator 1 is a protein belongs to the neuron navigator family and is expressed predominantly in the nervous system. The protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known.but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta. The abolition of mNAV1 causes loss of directionality in the leading processes of pontine-migrating cells, providing evidence for a role of mNAV1 in mediating Netrin-1-induced directional migration.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuron Navigator 1 (NAV1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuron Navigator 1 (NAV1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuron Navigator 1 (NAV1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuron Navigator 1 (NAV1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuron Navigator 1 (NAV1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuron Navigator 1 (NAV1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuron Navigator 1 (NAV1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuron Navigator 1 (NAV1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuron Navigator 1 (NAV1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuron Navigator 1 (NAV1) ELISA Kit Customized Service Offer
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  2. "Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans."Genomics 80:21-30(2002) [PubMed] [Europe PMC] [Abstract]
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