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Peripheral Myelin Protein 22 (PMP22)

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DSS; CMT1A; CMT1E; GAS3; HMSNIA; HNPP; Sp110; Growth arrest-specific protein 3

Peripheral Myelin Protein 22 (PMP22)
CCC C746
HGNC 9118
MGI 97631
PubMed 12244079
RGD 3359
UniProt Q01453
Wiki PMP22
Peripheral myelin protein 22, also known as PMP22, is a protein encoded by the PMP22 gene. Alternative splicing of this gene results in three transcript variants that encode the same protein.
The integral membrane protein encoded by this gene is a hydrophobic, tetraspan glycoprotein expressed mainly in Schwann cells and is a major component of compact myelin in the peripheral nervous system.Various mutations of the gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and Hereditary neuropathy with liability to pressure palsies (HNPP).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC746Hu01 Recombinant Peripheral Myelin Protein 22 (PMP22) Positive Control; Immunogen; SDS-PAGE; WB.
RPC746Hu02 Recombinant Peripheral Myelin Protein 22 (PMP22) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC746Hu01 Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
MAC746Hu21 Monoclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
Assay Kits SEC746Hu ELISA Kit for Peripheral Myelin Protein 22 (PMP22) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC746Mu01 Recombinant Peripheral Myelin Protein 22 (PMP22) Positive Control; Immunogen; SDS-PAGE; WB.
RPC746Mu02 Recombinant Peripheral Myelin Protein 22 (PMP22) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC746Mu01 Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
PAC746Mu02 Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
Assay Kits SEC746Mu ELISA Kit for Peripheral Myelin Protein 22 (PMP22) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC746Ra01 Recombinant Peripheral Myelin Protein 22 (PMP22) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC746Ra01 Polyclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
MAC746Ra21 Monoclonal Antibody to Peripheral Myelin Protein 22 (PMP22) WB; IHC; ICC; IP.
Assay Kits SEC746Ra ELISA Kit for Peripheral Myelin Protein 22 (PMP22) Enzyme-linked immunosorbent assay for Antigen Detection.
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  48. "T118M PMP22 mutation causes partial loss of function and HNPP-like neuropathy."Ann. Neurol. 59:358-364(2006) [PubMed] [Europe PMC] [Abstract]