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Phosducin (PDC)

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PhLP; MEKA; PHD; PhLOP; 33 kDa phototransducing protein

Phosducin (PDC)
CCC C751
HGNC 8759
MGI 98090
PubMed 19959875
RGD 3277
UniProt P20941
Wiki Phosducin
Phosducin, also known as PDC, is a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, Transducin will stay bound to the alpha subunit longer. This will increase the amount of time of visual excitation.
This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosducin (PDC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosducin (PDC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosducin (PDC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosducin (PDC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosducin (PDC) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosducin (PDC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosducin (PDC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosducin (PDC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosducin (PDC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosducin (PDC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosducin (PDC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosducin (PDC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosducin (PDC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosducin (PDC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosducin (PDC) ELISA Kit Customized Service Offer
  1. "Analysis of the human, bovine and rat 33-kDa proteins and cDNA in retina and pineal gland."Gene 91:209-215(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation and analysis of the human MEKA gene encoding a retina-specific protein."Biochem. Biophys. Res. Commun. 170:951-956(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Modulation of CRX transactivation activity by phosducin isoforms."Mol. Cell. Biol. 20:5216-5226(2000) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]