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Ribophorin I (RPN1)

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RPNI; OST1; RBPH1; Dolichyl-Diphosphooligosaccharide-Protein Glycosyltransferase Subunit 1; Dolichyl-diphosphooligosaccharide protein glycosyltransferase 67 kDa subunit

Ribophorin I (RPN1)
CCC C769
HGNC 10381
MGI 98084
PubMed 11447136
RGD 3594
UniProt P04843
Wiki RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 is a type I integral ribophorin membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.
This protein should not be confused with RPN1 of yeast, Drosophila, and C. elegans, which forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. The human version of this proteasome subunit is PSMD2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC769Hu01 Recombinant Ribophorin I (RPN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC769Hu02 Recombinant Ribophorin I (RPN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC769Hu03 Recombinant Ribophorin I (RPN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC769Hu04 Recombinant Ribophorin I (RPN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC769Hu01 Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
MAC769Hu22 Monoclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
PAC769Hu02 Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
PAC769Hu04 Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
PAC769Hu03 Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
LAC769Hu71 Biotin-Linked Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC.
Assay Kits SEC769Hu ELISA Kit for Ribophorin I (RPN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC769Mu01 Recombinant Ribophorin I (RPN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC769Mu01 Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IP.
LAC769Mu81 FITC-Linked Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC; IF.
LAC769Mu71 Biotin-Linked Polyclonal Antibody to Ribophorin I (RPN1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Ribophorin I (RPN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribophorin I (RPN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribophorin I (RPN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribophorin I (RPN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribophorin I (RPN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribophorin I (RPN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribophorin I (RPN1) ELISA Kit Customized Service Offer
  1. "Human ribophorins I and II: the primary structure and membrane topology of two highly conserved rough endoplasmic reticulum-specific glycoproteins."EMBO J. 6:75-82(1987) [PubMed] [Europe PMC] [Abstract]
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  8. "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis."J. Biol. Chem. 286:42937-42948(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]