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Reelin is a protein that helps regulate processes of neuronal migration and positioning in the developing brain. Besides this important role in early development, reelin continues to work in the adult brain. It modulates the synaptic plasticity by enhancing the induction and maintenance of long-term potentiation.
It also stimulates dendrite and dendritic spine development and regulates the continuing migration of neuroblasts generated in adult neurogenesis sites like subventricular and subgranular zones. It is found not only in the brain, but also in the spinal cord, blood, and other body organs and tissues. Reelin has been suggested to be implicated in pathogenesis of several brain diseases.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC775Hu01 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC775Hu03 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPC775Hu02 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPC775Hu04 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| RPC775Hu05 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAC775Hu01 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. |
| MAC775Hu22 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| PAC775Hu03 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| PAC775Hu02 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| PAC775Hu04 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu21 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu24 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu23 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu27 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu25 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| MAC775Hu29 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| Assay Kits | SEC775Hu | ELISA Kit for Reelin (RELN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC775Mu01 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC775Mu02 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAC775Mu01 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. |
| PAC775Mu02 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| Assay Kits | SEC775Mu | ELISA Kit for Reelin (RELN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPC775Ra01 | Recombinant Reelin (RELN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAC775Ra01 | Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. |
| LAC775Ra71 | Biotin-Linked Polyclonal Antibody to Reelin (RELN) | WB; IHC; ICC. | |
| MAC775Ra21 | Monoclonal Antibody to Reelin (RELN) | WB; IHC; ICC; IP. | |
| Assay Kits | SEC775Ra | ELISA Kit for Reelin (RELN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCC775Ra | CLIA Kit for Reelin (RELN) | Chemiluminescent immunoassay for Antigen Detection. |
- "The human reelin gene: isolation, sequencing, and mapping on chromosome 7."Genome Res. 7:157-164(1997) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
- "Evolutionarily conserved, alternative splicing of reelin during brain development."Exp. Neurol. 156:229-238(1999) [PubMed] [Europe PMC] [Abstract]
- "A decrease of reelin expression as a putative vulnerability factor in schizophrenia."Proc. Natl. Acad. Sci. U.S.A. 95:15718-15723(1998) [PubMed] [Europe PMC] [Abstract]
- "Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations."Nat. Genet. 26:93-96(2000) [PubMed] [Europe PMC] [Abstract]
- ErratumNat. Genet. 27:225-225(2001)
- "Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder." Mol. Psychiatry 6:150-159(2001) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]