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Translocation Protein 1 (TLOC1)

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Dtrp1; HTP1; SEC62

Translocation Protein 1 (TLOC1)
CCC C793
HGNC 11846
MGI 1916526
PubMed 10683767
RGD 1308862
UniProt Q99442
Wiki TLOC1
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane.
Translocation protein SEC62 and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocation Protein 1 (TLOC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocation Protein 1 (TLOC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocation Protein 1 (TLOC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocation Protein 1 (TLOC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocation Protein 1 (TLOC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocation Protein 1 (TLOC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocation Protein 1 (TLOC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocation Protein 1 (TLOC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocation Protein 1 (TLOC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocation Protein 1 (TLOC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocation Protein 1 (TLOC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocation Protein 1 (TLOC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocation Protein 1 (TLOC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocation Protein 1 (TLOC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocation Protein 1 (TLOC1) ELISA Kit Customized Service Offer
  1. "Identification of a human cDNA homologue to the Drosophila translocation protein 1 (Dtrp-1)."Biochem. Biophys. Res. Commun. 230:100-104(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Fine structure of the human translocation protein 1 (HTP1/TLOC1) gene."IUBMB Life 48:619-624(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Mammalian Sec61 is associated with Sec62 and Sec63."J. Biol. Chem. 275:14550-14557(2000) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]