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Tuftelin (TUFT)

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TUFT1

Tuftelin (TUFT)
CCC C829
HGNC 12422
MGI 109572
PubMed 9189622
RGD 1310373
UniProt Q9NNX1
Wiki Tuftelin
Tuftelin is an acidic phosphorylated glycoprotein found in tooth enamel. In humans, the Tuftelin protein is encoded by the TUFT1 gene.This protein is formed for a short time during amelogenesis. The function of tuftelins is under contention, but it is proposed that it acts to start the mineralization process of enamel during tooth development. Other significant proteins in enamel are amelogenins, enamelins, and ameloblastins.
The human encoding gene for tuftelin (TUFT1) was cloned by Profs. Dany Deutsch and Aharon Palmon from the Hebrew University-Hadassah School of Dental Medicine in Jerusalem.It is thought to play a major role in mineralization and structural organization of enamel.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC829Hu01 Recombinant Tuftelin (TUFT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC829Hu01 Polyclonal Antibody to Tuftelin (TUFT) WB; IHC; ICC; IP.
Assay Kits SEC829Hu ELISA Kit for Tuftelin (TUFT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC829Mu01 Recombinant Tuftelin (TUFT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC829Mu01 Polyclonal Antibody to Tuftelin (TUFT) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tuftelin (TUFT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tuftelin (TUFT) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tuftelin (TUFT) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tuftelin (TUFT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tuftelin (TUFT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tuftelin (TUFT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tuftelin (TUFT) ELISA Kit Customized Service Offer
  1. "The human tuftelin gene: cloning and characterization."Gene 279:181-196(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Mapping of the human tuftelin (TUFT1) gene to chromosome 1 by fluorescence in situ hybridization."Mamm. Genome 5:461-462(1994) [PubMed] [Europe PMC] [Abstract]
  7. "Sequencing of bovine enamelin ('tuftelin') a novel acidic enamel protein."J. Biol. Chem. 266:16021-16028(1991) [PubMed] [Europe PMC] [Abstract]