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Septin 1 (SEPT1)

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DIFF6; LARP; PNUTL3; SEP1; Peanut-like protein 3; Serologically defined breast cancer antigen NY-BR-24

Septin 1 (SEPT1)
CCC C839
HGNC 2879
MGI 1858916
PubMed 23087102
RGD 1307216
UniProt Q8WYJ6
Wiki SEPT1
Septin-1 is a member of the septin family of GTPases. This gene encodes a protein associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. In immunoblotting, SEPT1, together with other septins, was detected in normal human epidermis, SCC and DJM-1. In immunohistochemical analyses, SEPT1 was detected diffusely in the cytoplasm of human epidermal cells and eccrine gland epithelial cells, and the protein level was increased in some skin tumors. In DJM-1 cells, SEPT1 together with other members of SEPT2-subgroup, SEPT4 and SEPT5, was enriched in lamellipodia and the localization was dependent on the cortical actin structure. SEPT1 distribution at lamellipodia was also observed in melanoma B16 cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 1 (SEPT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 1 (SEPT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 1 (SEPT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 1 (SEPT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 1 (SEPT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 1 (SEPT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 1 (SEPT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 1 (SEPT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 1 (SEPT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 1 (SEPT1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 1 (SEPT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 1 (SEPT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 1 (SEPT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 1 (SEPT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 1 (SEPT1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  5. "Septin1, a new interaction partner for human serine/threonine kinase aurora-B."Biochem. Biophys. Res. Commun. 336:994-1000(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Expression profiling the human septin gene family."J. Pathol. 206:269-278(2005) [PubMed] [Europe PMC] [Abstract]
  7. "From midbody protein-protein interaction network construction to novel regulators in cytokinesis."J. Proteome Res. 8:4943-4953(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]