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CDP Diacylglycerol Synthase 2 (CDS2)

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Phosphatidate Cytidylyltransferase 2; CDP-diglyceride pyrophosphorylase 2; phosphatidate cytidylyltransferase 2

CDP Diacylglycerol Synthase 2 (CDS2)
CCC C854
HGNC 1801
MGI 1332236
PubMed 9889000
RGD 621186
UniProt O95674
Wiki CDS2
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity.
Phosphatidate cytidylyltransferase 2 isan enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CDP Diacylglycerol Synthase 2 (CDS2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CDP Diacylglycerol Synthase 2 (CDS2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CDP Diacylglycerol Synthase 2 (CDS2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CDP Diacylglycerol Synthase 2 (CDS2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CDP Diacylglycerol Synthase 2 (CDS2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CDP Diacylglycerol Synthase 2 (CDS2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CDP Diacylglycerol Synthase 2 (CDS2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CDP Diacylglycerol Synthase 2 (CDS2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CDP Diacylglycerol Synthase 2 (CDS2) CLIA Kit Customized Service Offer
n/a ELISA Kit for CDP Diacylglycerol Synthase 2 (CDS2) ELISA Kit Customized Service Offer
  1. "Identification and characterization of CDS2, a mammalian homolog of the Drosophila CDP-diacylglycerol synthase gene."Genomics 55:68-77(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes."Genomics 54:140-144(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]