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Fibroblast Growth Factor 14 (FGF14)

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FHF4; SCA27; Fibroblast growth factor homologous factor 4

Fibroblast Growth Factor 14 (FGF14)
CCC C916
HGNC 3671
MGI 109189
PubMed 23831029
RGD 620165
UniProt Q92915
Wiki FGF14
Fibroblast growth factor 14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.
SCA27 is an autosomal dominant cerebellar ataxia (ADCA). It is a slowly progressive disorder, with onset in late-childhood to early adulthood, characterized by ataxia with tremor, orofacial dyskinesia, psychiatric symptoms and cognitive deficits.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins APC916Hu01 Active Fibroblast Growth Factor 14 (FGF14) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor 14 (FGF14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor 14 (FGF14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fibroblast Growth Factor 14 (FGF14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor 14 (FGF14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor 14 (FGF14) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fibroblast Growth Factor 14 (FGF14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fibroblast Growth Factor 14 (FGF14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fibroblast Growth Factor 14 (FGF14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fibroblast Growth Factor 14 (FGF14) ELISA Kit Customized Service Offer
  1. "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development."Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia." Proc. Natl. Acad. Sci. U.S.A. 99:13675-13680(2002) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebellar (sic) ataxia."Am. J. Hum. Genet. 72:191-199(2003) [PubMed] [Europe PMC] [Abstract]
  6. ErratumAm. J. Hum. Genet. 72:1078-1078(2003)
  7. "Mutation analysis in the fibroblast growth factor 14 gene: frameshift mutation and polymorphisms in patients with inherited ataxias."Eur. J. Hum. Genet. 13:118-120(2005) [PubMed] [Europe PMC] [Abstract]
  8. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]