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Cannabinoid Receptor 1, Brain (CNR1)

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CANN6; CB-R; CB1; CB1A; CB1K5; CNR

Cannabinoid Receptor 1, Brain (CNR1)
CCC C950
HGNC 2159
MGI 104615
PubMed 9106242
RGD 2369
UniProt P21554
Wiki CNR1
The cannabinoid receptor type 1 is a G protein-coupled cannabinoid receptor that is found in the brain and is activated by the psychoactive drug cannabis and its active compound THC and by a group of endocannabinoid neurotransmitters including anandamide.The CB1 receptor is encoded by the gene or CNR1. Two transcript variants encoding different isoforms have been described for this gene.
CNR1 orthologs have been identified in most mammals.CB1 receptors are thought to be the most widely expressed G protein-coupled receptors in the brain. The inverse agonist MK-9470 makes it possible to produce in vivo images of the distribution of CB1 receptors in the human brain with positron emission tomography.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC950Hu01 Recombinant Cannabinoid Receptor 1, Brain (CNR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC950Hu01 Polyclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) WB; IHC; ICC; IP.
MAC950Hu22 Monoclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) WB; IHC; ICC; IP.
Assay Kits SEC950Hu ELISA Kit for Cannabinoid Receptor 1, Brain (CNR1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cannabinoid Receptor 1, Brain (CNR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cannabinoid Receptor 1, Brain (CNR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cannabinoid Receptor 1, Brain (CNR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC950Ra01 Recombinant Cannabinoid Receptor 1, Brain (CNR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC950Ra01 Polyclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) WB; IHC; ICC; IP.
MAC950Ra21 Monoclonal Antibody to Cannabinoid Receptor 1, Brain (CNR1) WB; IHC; ICC; IP.
Assay Kits SEC950Ra ELISA Kit for Cannabinoid Receptor 1, Brain (CNR1) Enzyme-linked immunosorbent assay for Antigen Detection.
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  9. "Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling."Br. J. Pharmacol. 165:2635-2651(2012) [PubMed] [Europe PMC] [Abstract]
  10. "Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity."Protein Sci. 11:2526-2531(2002) [PubMed] [Europe PMC] [Abstract]