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Transforming Growth Factor Beta Receptor II (TGFbR2)

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Transforming Growth Factor Beta Receptor II (TGFbR2)
CCC C972
HGNC 11773
MGI 98729
PubMed 18781618
RGD 69651
UniProt P37173
Wiki TGFBR2
TGFBR2 is a tumor suppressor gene.The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC972Hu01 Recombinant Transforming Growth Factor Beta Receptor II (TGFbR2) Positive Control; Immunogen; SDS-PAGE; WB.
APC972Hu01 Active Transforming Growth Factor Beta Receptor II (TGFbR2) Cell culture; Activity Assays.
Antibodies PAC972Hu01 Polyclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) WB; IHC; ICC; IP.
MAC972Hu22 Monoclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) WB; IHC; ICC; IP.
PAC972Hu02 Polyclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) WB; IHC; ICC; IP.
Assay Kits SEC972Hu ELISA Kit for Transforming Growth Factor Beta Receptor II (TGFbR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC972Mu01 Recombinant Transforming Growth Factor Beta Receptor II (TGFbR2) Positive Control; Immunogen; SDS-PAGE; WB.
RPC972Mu02 Recombinant Transforming Growth Factor Beta Receptor II (TGFbR2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC972Mu01 Polyclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) WB; IHC; ICC; IP.
PAC972Mu02 Polyclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) WB; IHC; ICC; IP.
Assay Kits SEC972Mu ELISA Kit for Transforming Growth Factor Beta Receptor II (TGFbR2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transforming Growth Factor Beta Receptor II (TGFbR2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transforming Growth Factor Beta Receptor II (TGFbR2) Polyclonal Antibody Customized Service Offer
Assay Kits SEC972Ra ELISA Kit for Transforming Growth Factor Beta Receptor II (TGFbR2) Enzyme-linked immunosorbent assay for Antigen Detection.
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