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Asparaginyl tRNA Synthetase (NARS)

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AsnRS; NARS1; KS; Asparagine tRNA Ligase 1,Cytoplasmic

Asparaginyl tRNA Synthetase (NARS)
CCC C995
HGNC 7643
MGI 1917473
PubMed 24036469
RGD 1307238
UniProt O43776
Wiki NARS_(gene
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.
Hybrids selected at 39 degrees C required the presence of human chromosome 18. Temperature-resistant hybrid cells contained 2 forms of ASNRS: 1 highly thermal resistant, like the human enzyme, and 1 highly thermolabile, like the CHO mutant enzyme. The deduced 548-amino acid protein has a predicted molecular mass of 62.9 kD and shares 53% sequence identity with the S. cerevisiae homolog.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC995Hu01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC995Hu01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB,IHC
Assay Kits n/a CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asparaginyl tRNA Synthetase (NARS) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC995Mu01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asparaginyl tRNA Synthetase (NARS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Asparaginyl tRNA Synthetase (NARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Asparaginyl tRNA Synthetase (NARS) ELISA Kit Customized Service Offer
  1. "Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen."Nucleic Acids Res. 26:521-524(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Human asparaginyl-tRNA synthetase: molecular cloning and the inference of the evolutionary history of Asx-tRNA synthetase family."Nucleic Acids Res. 26:5045-5051(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]