Collagen Type XXVIII (COL28)

Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain.COL28A1 belongs to a class of collagens containing von Willebrand factor (VWF) type A (VWA) domains (Veit et al., 2006).Veit et al. (2006) determined that the COL28A1 gene spans 178 kb and contains 34 coding exons and 1 upstream noncoding exon.

The mouse Col28a1 gene spans 195 kb and has the same organization as human COL28A1.By genomic sequence analysis Veit et al. (2006) mapped the COL28A1 gene to chromosome 7p21.3. They mapped the mouse Col28a1 gene to a region of chromosome 6A1 that shares homology of synteny with human chromosome 7p21.3.