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Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9)

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CHR-NA9; CHRN-A9; N-AChRA9; NAChRA9; N-AChR-A9; Neuronal Acetylcholine Receptor Alpha 9

Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9)
CCC D147
HGNC 14079
MGI 1202403
PubMed 15531379
RGD 621534
UniProt Q9UGM1
Wiki CHRNA9
Neuronal acetylcholine receptor subunit alpha-9 is is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels.
This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.Selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD147Hu01 Recombinant Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cholinergic Receptor, Nicotinic, Alpha 9 (CHRNa9) ELISA Kit Customized Service Offer
  1. "A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit."Mol. Pharmacol. 61:150-159(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Chromosome location and characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) gene."Cytogenet. Genome Res. 98:154-159(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Novel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunity."Am. J. Pathol. 157:1377-1391(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes."Life Sci. 76:263-280(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Crystal structures of free and antagonist-bound states of human alpha9 nicotinic receptor extracellular domain."Nat. Struct. Mol. Biol. 21:976-980(2014) [PubMed] [Europe PMC] [Abstract]