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Cytochrome b5, Form A (CYB5A)

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CYB5; MCB5

Cytochrome b5, Form A (CYB5A)
CCC D292
HGNC 2570
MGI 1926952
PubMed 24301457
RGD 620558
UniProt P00167
Wiki CYB5A
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It has two isoforms produced by alternative splicing. Isoform 1 is bound to the cytoplasmic side of the endoplasmic reticulum. It has a C-terminal transmembrane alpha-helix. Isoform 2 was found in cytoplasm. Defects in CYB5A are the cause of type IV hereditary methemoglobinemia.
The derived amino acid sequence showed that the previous designation of several amino acids was in error. Liver and erythrocyte cytochrome b5 isoforms have the same amino acid sequence except at position 98, which is thr and pro for liver and erythrocyte proteins, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome b5, Form A (CYB5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome b5, Form A (CYB5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome b5, Form A (CYB5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome b5, Form A (CYB5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome b5, Form A (CYB5A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome b5, Form A (CYB5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome b5, Form A (CYB5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome b5, Form A (CYB5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome b5, Form A (CYB5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome b5, Form A (CYB5A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome b5, Form A (CYB5A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome b5, Form A (CYB5A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome b5, Form A (CYB5A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome b5, Form A (CYB5A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome b5, Form A (CYB5A) ELISA Kit Customized Service Offer
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  2. "The human liver and reticulocyte cytochrome b5 mRNAs are products from a single gene."Biochem. Biophys. Res. Commun. 178:38-44(1991) [PubMed] [Europe PMC] [Abstract]
  3. "The isolation and characterization of the human cytochrome b5 gene."Biochem. Biophys. Res. Commun. 209:894-900(1995) [PubMed] [Europe PMC] [Abstract]
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  8. "Cytochrome b5 from a normal human liver. Isolation and the partial amino acid sequence."J. Biol. Chem. 247:2242-2245(1972) [PubMed] [Europe PMC] [Abstract]
  9. "Structural studies of cytochrome b5. 3. Sequential studies on human liver cytochrome b5."J. Biochem. 74:985-1002(1973) [PubMed] [Europe PMC] [Abstract]
  10. "Structure of cytochrome b5 and its topology in the microsomal membrane."Biochim. Biophys. Acta 997:121-130(1989) [PubMed] [Europe PMC] [Abstract]
  11. "A splicing mutation in the cytochrome b5 gene from a patient with congenital methemoglobinemia and pseudohermaphrodism."Hum. Genet. 93:568-570(1994) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]