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Cytochrome P450 2A6 (CYP2A6)

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CYP2A; CYP2A3; CPA6; CYPIIA6; Cytochrome P450 Family 2 Subfamily A Polypeptide 6; 1,4-cineole 2-exo-monooxygenase; Coumarin 7-hydroxylase

Cytochrome P450 2A6 (CYP2A6)
CCC D298
HGNC 2610
PubMed 16402086
UniProt P11509
Wiki CYP2A6
CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome P450 2A6 (CYP2A6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome P450 2A6 (CYP2A6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome P450 2A6 (CYP2A6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome P450 2A6 (CYP2A6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome P450 2A6 (CYP2A6) ELISA Kit Customized Service Offer
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