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Aldolase B, Fructose Bisphosphate (ALDOB)

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ALDO-BL; Liver-type aldolase

Aldolase B, Fructose Bisphosphate (ALDOB)
CCC D319
HGNC 417
MGI 87995
PubMed 15880727
RGD 2090
UniProt P05062
Wiki ALDOB
Aldolase B is an isoenzyme of fructose 1,6-bisphosphate aldolase (aldolase A), which is also capable of cleaving fructose 1-phosphate to form glyceraldehyde and dihydroxyacetone phosphate (DHAP). The reaction is reversible. Also known as Aldolase (Class I), it is found in the liver and kidney.
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13 ) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Defects of aldolase B cause fructose 1-phosphate to accumulate in tissues which contain fructokinase, a condition known as hereditary fructose intolerance.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD319Hu01 Recombinant Aldolase B, Fructose Bisphosphate (ALDOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD319Hu01 Polyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) WB; IHC; ICC; IP.
MAD319Hu21 Monoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) WB; IHC; ICC; IP.
Assay Kits SED319Hu ELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aldolase B, Fructose Bisphosphate (ALDOB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aldolase B, Fructose Bisphosphate (ALDOB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD319Ra01 Recombinant Aldolase B, Fructose Bisphosphate (ALDOB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD319Ra01 Polyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) WB; IHC; ICC; IP.
MAD319Ra21 Monoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB) WB; IHC; ICC; IP.
Assay Kits SED319Ra ELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB) Enzyme-linked immunosorbent assay for Antigen Detection.
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  18. "A new aldolase B variant, N334K, is a common cause of hereditary fructose intolerance in Yugoslavia."Nucleic Acids Res. 18:1925-1925(1990) [PubMed] [Europe PMC] [Abstract]
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  21. "Molecular analysis of the aldolase B gene in patients with hereditary fructose intolerance from Spain."J. Med. Genet. 39:E56-E56(2002) [PubMed] [Europe PMC] [Abstract]
  22. "Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene."Hum. Mutat. 24:534-534(2004) [PubMed] [Europe PMC] [Abstract]
  23. "The spectrum of aldolase B (ALDOB) mutations and the prevalence of hereditary fructose intolerance in Central Europe."Hum. Mutat. 25:594-594(2005) [PubMed] [Europe PMC] [Abstract]