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Kruppel Like Factor 3, Basic (KLF3)

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BKLF; TEF-2; Basic krueppel-like factor; CACCC-box-binding protein BKLF

Kruppel Like Factor 3, Basic (KLF3)
CCC D366
HGNC 16516
MGI 1342773
PubMed 23633521
RGD 1593290
UniProt P57682
Wiki KLF3
The Krüppel-like family of transcription factors (Klfs),have been extensively studied for their roles in cell proliferation, differentiation and survival, especially in the context of cancer . All KLF family members are characterised by their three Cys2 His2 zinc fingers located at the C-terminus, separated by a highly conserved H/C link, DNA binding studies demonstrated that the KLFs have similar affinities for different GC-rich sites, or sites with CACCC homology, and can compete with each other for the occupation of such sites.
The human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kruppel Like Factor 3, Basic (KLF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kruppel Like Factor 3, Basic (KLF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kruppel Like Factor 3, Basic (KLF3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kruppel Like Factor 3, Basic (KLF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kruppel Like Factor 3, Basic (KLF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kruppel Like Factor 3, Basic (KLF3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kruppel Like Factor 3, Basic (KLF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kruppel Like Factor 3, Basic (KLF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kruppel Like Factor 3, Basic (KLF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kruppel Like Factor 3, Basic (KLF3) ELISA Kit Customized Service Offer
  1. "cDNA cloning, subcellular localization and tissue expression of a new human Kruppel-like transcription factor: human basic Kruppel-like factor (hBKLF)."Yi Chuan Xue Bao 30:1-9(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]