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Placental Thrombin Inhibitor (PTI)

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SERPINB6; CAP; PI6; SPI3; Serpin Peptidase Inhibitor Clade B Member 6; Cytoplasmic antiproteinase; Peptidase inhibitor 6

Placental Thrombin Inhibitor (PTI)
CCC D388
HGNC 8950
MGI 103123
PubMed 8415716
RGD 735108
UniProt P35237
Wiki SERPINB6
PTI is a member of an emerging class of intracellular serpins.On the basis of its interaction with thrombin, through which it was discovered, the inhibitor was operationally named the placental thrombin inhibitor (PTI). Amino acid sequence comparisons suggested that its reactive center is located at arg341 and cys342, that it lacks a classic N-terminal signal sequence, and that it has the highest degree of similarity to intracellular serine proteinase inhibitors (serpins), such as the human monocyte/neutrophil elastase inhibitor (ELANH2). Analysis of human tissue mRNA indicated that PTI is expressed widely, with the highest levels in cardiac and skeletal muscle and placenta.Spi3, is developmentally regulated, and that, unlike the situation in the human, Spi3 is absent from the mouse placenta.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD388Hu01 Recombinant Placental Thrombin Inhibitor (PTI) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD388Hu01 Polyclonal Antibody to Placental Thrombin Inhibitor (PTI) WB; IHC; ICC; IP.
MAD388Hu21 Monoclonal Antibody to Placental Thrombin Inhibitor (PTI) WB; IHC; ICC; IP.
Assay Kits SED388Hu ELISA Kit for Placental Thrombin Inhibitor (PTI) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Placental Thrombin Inhibitor (PTI) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Placental Thrombin Inhibitor (PTI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Placental Thrombin Inhibitor (PTI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Placental Thrombin Inhibitor (PTI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Placental Thrombin Inhibitor (PTI) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Placental Thrombin Inhibitor (PTI) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Placental Thrombin Inhibitor (PTI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Placental Thrombin Inhibitor (PTI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Placental Thrombin Inhibitor (PTI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Placental Thrombin Inhibitor (PTI) ELISA Kit Customized Service Offer
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