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Myosin Heavy Chain 10, Non Muscle (MYH10)

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NMMHCB; Cellular myosin heavy chain, type B; Myosin heavy chain, non-muscle IIb

Myosin Heavy Chain 10, Non Muscle (MYH10)
CCC D423
HGNC 7568
MGI 1930780
PubMed 22677128
RGD 71000
UniProt P35580
Wiki MYH10
Myh10 was abundantly expressed in mouse brain and testis. It was also expressed in heart, lung, liver, and kidney, but not in skeletal muscle or spleen.Actin-activated MgATPase activity was decreased in MYH10 with either an asn97-to-lysine substitution, which is homologous to the N93K mutation in MYH9 that causes May-Hegglin anomaly , or an arg709-to-cysteine substitution, which causes developmental defects in brain and heart when present in mouse Myh10. The ability of MYH10 heavy meromyosin to support the movement of actin filaments over an MYH10-coated surface was reduced in heavy meromyosin with the N97K mutation and eliminated with the R709C mutation. Kinetic analysis indicated that the R709C mutation resulted in extremely tight affinity between MYH10 heavy meromyosin and ADP, reducing the rate of ADP release.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD423Hu01 Recombinant Myosin Heavy Chain 10, Non Muscle (MYH10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD423Hu01 Polyclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) WB; IHC; ICC; IP.
MAD423Hu21 Monoclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) WB; IHC; ICC; IP.
Assay Kits SED423Hu ELISA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin Heavy Chain 10, Non Muscle (MYH10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) Polyclonal Antibody Customized Service Offer
Assay Kits SED423Mu ELISA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin Heavy Chain 10, Non Muscle (MYH10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin Heavy Chain 10, Non Muscle (MYH10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Heavy Chain 10, Non Muscle (MYH10) ELISA Kit Customized Service Offer
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