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Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4)

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GT1; ALC1; AMLC; Myosin light chain alkali GT-1 isoform

Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4)
CCC D427
HGNC 7585
MGI 97267
UniProt P12829
Wiki MYL4
Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
By Southern blot analysis of DNA from somatic cell hybrids, Cohen-Haguenauer et al. (1989) assigned the MYL4 gene (which codes the atrial/fetal muscle isoform of myosin alkali light chains) to chromosome 17. The corresponding gene in the mouse has been assigned to chromosome 11.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD427Hu01 Recombinant Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD427Hu01 Polyclonal Antibody to Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD427Mu01 Recombinant Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD427Mu01 Polyclonal Antibody to Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4) ELISA Kit Customized Service Offer
  1. "A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in adult atria."Eur. J. Biochem. 178:53-60(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones."J. Biol. Chem. 263:13930-13936(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Human embryonic/atrial myosin alkali light chain gene: characterization, sequence, and chromosomal location."Genomics 7:289-293(1990) [PubMed] [Europe PMC] [Abstract]
  4. "Heterogenic mRNAs with an identical protein-coding region of the human embryonic myosin alkali light chain in skeletal muscle cells."J. Mol. Biol. 211:505-513(1990) [PubMed] [Europe PMC] [Abstract]
  5. "The human embryonic myosin alkali light chain gene: use of alternative promoters and 3' non-coding regions."Nucleic Acids Res. 19:1497-1504(1991) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Alkali myosin light chains in man are encoded by a multigene family that includes the adult skeletal muscle, the embryonic or atrial, and nonsarcomeric isoforms."Gene 66:135-146(1988) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]