Class III myosins are actin-dependent motor proteins that contain amino-terminal kinase domains and are expressed in photoreceptors. Using BLAST analysis with the sequence of MYO3A as query, followed by RACE on human retinal cDNA, Dose and Burnside (2002) cloned a full-length MYO3B cDNA and revealed alternative 3-prime splice variants. Similar to other class III myosins, MYO3B contains an N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3B gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis showed expression of a 7-kb MYO3B transcript in human retina, but not in an RPE cell line; two 6- and 7-kb MYO3B transcripts in kidney; and a 4-kb transcript in testis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Myosin IIIB (MYO3B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Myosin IIIB (MYO3B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Myosin IIIB (MYO3B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Myosin IIIB (MYO3B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Myosin IIIB (MYO3B) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Myosin IIIB (MYO3B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Myosin IIIB (MYO3B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Myosin IIIB (MYO3B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Myosin IIIB (MYO3B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Myosin IIIB (MYO3B) | ELISA Kit Customized Service Offer |
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