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Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)

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HIF-1beta; bHLHe2; Hypoxia Inducible Factor 1 Beta; Class E basic helix-loop-helix protein 2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta

Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)
CCC D470
HGNC 700
MGI 88071
PubMed 16941684
RGD 2153
UniProt P27540
Wiki ARNT
Aryl hydrocarbon receptor nuclear translocator protein forms a complex with ligand-bound aryl hydrocarbon receptor (AhR), and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1). A t(1;12)(q21;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Three alternatively spliced variants encoding different isoforms have been described for this gene.
The aryl hydrocarbon receptor (AhR) is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the aryl hydrocarbon receptor is complexed to heat shock protein 90.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD470Hu01 Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD470Hu01 Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
MAD470Hu21 Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
MAD470Hu22 Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
MAD470Hu24 Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
MAD470Hu27 Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
Assay Kits SED470Hu ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD470Mu01 Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Positive Control; Immunogen; SDS-PAGE; WB.
RPD470Mu02 Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD470Mu01 Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
PAD470Mu02 Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) WB; IHC; ICC; IP.
Assay Kits SED470Mu ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) CLIA Kit Customized Service Offer
n/a ELISA Kit for Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) ELISA Kit Customized Service Offer
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  10. "Casein kinase 1 regulates human hypoxia-inducible factor HIF-1."J. Cell Sci. 123:2976-2986(2010) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]