Mitogen Activated Protein Kinase 6 (MAPK6)
[Edit]ERK3; HsT17250; PRKM6; p97MAPK; Extracellular signal-regulated kinase 3; MAP kinase isoform p97
Mitogen-activated protein kinase 6 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals.
This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD566Hu01 | Recombinant Mitogen Activated Protein Kinase 6 (MAPK6) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD566Hu01 | Polyclonal Antibody to Mitogen Activated Protein Kinase 6 (MAPK6) | WB; IHC |
Assay Kits | n/a | CLIA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Mitogen Activated Protein Kinase 6 (MAPK6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Mitogen Activated Protein Kinase 6 (MAPK6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Mitogen Activated Protein Kinase 6 (MAPK6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Mitogen Activated Protein Kinase 6 (MAPK6) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Mitogen Activated Protein Kinase 6 (MAPK6) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Mitogen Activated Protein Kinase 6 (MAPK6) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Mitogen Activated Protein Kinase 6 (MAPK6) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3."Mol. Cell. Biol. 14:8202-8211(1994) [PubMed] [Europe PMC] [Abstract]
- "Primary structure, expression and chromosomal locus of a human homolog of rat ERK3."Oncogene 13:1575-1579(1996) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "Human protein factory for converting the transcriptome into an in vitro-expressed proteome." Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome."Mol. Cell. Biol. 24:6140-6150(2004) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway."J. Biol. Chem. 286:6470-6478(2011) [PubMed] [Europe PMC] [Abstract]
- "Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes."Mol. Cell. Biol. 32:3095-3106(2012) [PubMed] [Europe PMC] [Abstract]
- "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]