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Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1)

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MIP1; SIN1; SIN1b; SIN1g; Stress-Activated Protein Kinase-Interacting 1; Stress-activated map kinase-interacting protein 1; Target of rapamycin complex 2 subunit MAPKAP1

Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1)
CCC D581
HGNC 18752
MGI 2444554
PubMed 18687895
RGD 1305363
UniProt Q9BPZ7
Wiki MAPKAP1
Target of rapamycin complex 2 subunit MAPKAP1 is a protein similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.
The deduced 522-amino acid protein has a nuclear localization signal, 2 bipartite nuclear localization signals, a peroxisomal targeting signal, and a PEST motif for rapid protein degradation. Comparison of SIN1 with homologs from various species revealed a short, highly conserved region, designated Box1, located within a larger conserved domain, designated CRIM (conserved region in middle).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD581Hu01 Recombinant Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD581Hu01 Polyclonal Antibody to Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) WB; IHC; ICC; IP.
Assay Kits SED581Hu ELISA Kit for Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase Associated Protein 1 (MAPKAP1) ELISA Kit Customized Service Offer
  1. "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene."Gene 339:17-23(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation."Mol. Cell. Biol. 25:5955-5964(2005) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]