≡

Protein Tyrosine Phosphatase Receptor Type G (PTPRG)

[Edit]

PTPR-G; HPTPG; PTPG; R-PTP-GAMMA; RPTPG; Receptor-type tyrosine-protein phosphatase gamma

Protein Tyrosine Phosphatase Receptor Type G (PTPRG)
CCC D602
HGNC 9671
MGI 97814
PubMed 20651337
RGD 620774
UniProt P23470
Wiki PTPRG
Receptor-type tyrosine-protein phosphatase gamma is member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD602Hu01 Recombinant Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD602Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) WB; IHC; ICC; IP.
MAD602Hu21 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) WB; IHC; ICC; IP.
Assay Kits SED602Hu ELISA Kit for Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Polyclonal Antibody Customized Service Offer
Assay Kits SED602Mu ELISA Kit for Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type G (PTPRG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit Customized Service Offer
  1. "Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases."Mol. Cell. Biol. 13:1497-1506(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation."Genomics 32:225-235(1996) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Structural diversity and evolution of human receptor-like protein tyrosine phosphatases."EMBO J. 9:3241-3252(1990) [PubMed] [Europe PMC] [Abstract]
  7. "Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain."Proc. Natl. Acad. Sci. U.S.A. 87:7000-7004(1990) [PubMed] [Europe PMC] [Abstract]
  8. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Large-scale structural analysis of the classical human protein tyrosine phosphatome."Cell 136:352-363(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Crystal structure of the human receptor phosphatase PTPRG."Submitted (JUL-2006) to the PDB data bank
  12. "Structural genomics of protein phosphatases."Submitted (MAR-2008) to the PDB data bank
  13. "The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules."Proc. Natl. Acad. Sci. U.S.A. 107:2443-2448(2010) [PubMed] [Europe PMC] [Abstract]