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ATP Binding Cassette Transporter C13 (ABCC13)

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ABC-C13; PRED6; C21orf73; Putative ATP-binding cassette sub-family C member 13

ATP Binding Cassette Transporter C13 (ABCC13)
CCC D633
HGNC 16022
PubMed 15203202
UniProt Q9NSE7
Wiki ABCC13
Putative ATP-binding cassette transporter sub-family C member 13 is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.
Highest expression in fetal liver and fetal spleen. In the adult, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD633Hu01 Recombinant ATP Binding Cassette Transporter C13 (ABCC13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD633Hu01 Polyclonal Antibody to ATP Binding Cassette Transporter C13 (ABCC13) WB; IHC; ICC; IP.
MAD633Hu21 Monoclonal Antibody to ATP Binding Cassette Transporter C13 (ABCC13) WB; IHC; ICC; IP.
Assay Kits SED633Hu ELISA Kit for ATP Binding Cassette Transporter C13 (ABCC13) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver."Biochem. Biophys. Res. Commun. 299:410-417(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages."Genomics 84:34-46(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms."Gene 312:41-50(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis."Genomics 79:833-843(2002) [PubMed] [Europe PMC] [Abstract]
  6. "An unappreciated role for RNA surveillance."Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]