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ATP Binding Cassette Transporter D2 (ABCD2)

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ABC-D2; ABC39; ALDL1; ALDR; ALDRP; hALDR; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ATP-binding cassette sub-family D member 2

ATP Binding Cassette Transporter D2 (ABCD2)
CCC D652
HGNC 66
MGI 1349467
PubMed 21790923
RGD 69244
UniProt Q9UBJ2
Wiki ABCD2
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATP Binding Cassette Transporter D2 (ABCD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATP Binding Cassette Transporter D2 (ABCD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATP Binding Cassette Transporter D2 (ABCD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter D2 (ABCD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter D2 (ABCD2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD652Mu01 Recombinant ATP Binding Cassette Transporter D2 (ABCD2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD652Mu01 Polyclonal Antibody to ATP Binding Cassette Transporter D2 (ABCD2) WB; IHC
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter D2 (ABCD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter D2 (ABCD2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATP Binding Cassette Transporter D2 (ABCD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATP Binding Cassette Transporter D2 (ABCD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATP Binding Cassette Transporter D2 (ABCD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter D2 (ABCD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter D2 (ABCD2) ELISA Kit Customized Service Offer
  1. "A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern."Proc. Natl. Acad. Sci. U.S.A. 93:1265-1269(1996) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter."Biochem. Biophys. Res. Commun. 239:261-264(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy."Biochem. Biophys. Res. Commun. 258:436-442(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters."J. Biol. Chem. 274:32738-32743(1999) [PubMed] [Europe PMC] [Abstract]
  7. "Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p."Biochem. Biophys. Res. Commun. 271:144-150(2000) [PubMed] [Europe PMC] [Abstract]
  8. "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."J. Cell Biol. 148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
  9. "Core signaling pathways in human pancreatic cancers revealed by global genomic analyses." Science 321:1801-1806(2008) [PubMed] [Europe PMC] [Abstract]